Call NANO AR 20-2024 PI Development of nano micro engineered devices for applications in peripheral nervous system pathological models

Job title:

Call NANO AR 20-2024 PI Development of nano micro engineered devices for applications in peripheral nervous system pathological models

Company:

Job description

Offer DescriptionThe ENGInerve project aims to develop and validate biomimetic and active nano micro engineered devices, to allow the characteristic polarized growth of peripheral neurons in a soft
environment and to stimulate them with sensory-like mechanical stimuli. The devices will combine a modulation of nano/micro-topographical cues, mechanical properties, biochemical cues, and active electro-mechanical stimuli. We aim to develop and tune our devices: as platforms to study in vitro the behavior of peripheral neurons from a neurodevelopmental disorder at the molecular level: we will investigate the peripheral neurons’
functioning in Angelman Syndrome, to identify eventual alterations underlying the AS behavioral and somatosensory dysfunctions; as scaffolds for repairing injured peripheral nerves and stimulating their intrinsic regenerative capability.RequirementsAdditional InformationEligibility criteriaMaster degree in Biology, Chemistry and pharmaceutical technologies, Biotechnology, Material Science, Biomedical Engineering, Biotechnology or similar topics; PhD in Biochemistry, Biotechnology, Biophysics, Nanoscience, Translational medicine, Biomedical Engineering, Biology, Neuroscience, or similar topics; at least 2 years of post-doctoral experience documented with publications. Experience in at least some activities/topics: Expertise in set up and culture of neuronal cell lines and primary murine neurons; cellular assays; experience in mechanobiology, expertise in neurodevelopmental pathological models, in Angelman Syndrome – Experience in preparation, processing and analysis of cells, Expertise in molecular biology and biochemistry, Confocal microscopy on live and fixed cell samples – Expertise in the development and use of advanced devices for cell culture: devices based on acoustic waves, soft lithography, solvent casting; English and some knowledge of ItalianEligible destination country/ies for fellows:

• Italy

Eligibility of fellows: country/ies of residence:

• EUROPE

Eligibility of fellows: nationality/ies:

• EUROPE

Selection processSelected candidates will be invited for an interview that will be held on May 22 2024, h. 11.00 a.m. by videoconference.Website for additional job detailsWork Location(s)Number of offers available 1 Company/Institute CNR – Istituto di Nanoscienze Country Italy GeofieldWhere to apply E-mailprotocollo.nano@pec.cnr.itContact CityPisa WebsiteSTATUS: EXPIRED

Expected salary

Location

Pisa

Job date

Sat, 20 Apr 2024 07:39:57 GMT

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