Post-doctorate (M/W) Design of specific chiral monomers and polymers

CNRS

vacanciesin.eu


7 Dec 2023
Job Information

Organisation/Company
CNRS
Department
Laboratoire de chimie des polymères organiques
Research Field
Chemistry » Physical chemistry
Physics » Chemical physics
Physics » Biophysics
Researcher Profile
Recognised Researcher (R2)
Country
France
Application Deadline
27 Dec 2023 – 23:59 (UTC)
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
35
Offer Starting Date
1 Feb 2024
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

Asymmetry is a fundamental quality leading often to chirality. Though most amino-acids are L-enantiomers, D-amino acids (D-AA) are present in mammals and humans and involved in vital mechanisms from neuronal function to glucose homeostasis. Alterations in their levels have been linked to major chronic diseases such as Alzheimer’s or diabetes. Detailed knowledge on D-AA is lacking, as their detection is currently cumbersome, technically highly demanding and requires sample preparation thus precluding meaningful continuous monitoring. Based on our expertise, we propose here a novel sensor for continuous monitoring, combining advantages of organic electrochemical transistors (OECT), such as low noise and good cell interfacing, with diastereomeric interactions between newly synthesized conducting polymer probes and analyte. Electropolymerization will provide elegant means to enhance detection limits and kinetics and to prepare multiparametric chips for concomitant detection of several enantiomers.

Here, we will design specific Thiophene or EDOT-based monomers bearing on a subunit the stereoisomeric counterpart of the AA we want to detect, for subsequent electropolymerization and integration in OECTs with our ANR partners. Polymer equivalents can be prepared by other means.

The post-doctoral position is part of an ANR CHIRA-SENSEO project (2024-2027) and will be carried out at the Laboratoire de Chimie des Polymères Organiques (LCPO, UMR 5629 CNRS-Université de Bordeaux-Bordeaux INP) within Team 4: Polymers for electronics, energy and information. All the LCPO’s infrastructures and skills in terms of functional polymers engineering will be made available.

Requirements

Research Field
Chemistry
Education Level
PhD or equivalent

Research Field
Physics
Education Level
PhD or equivalent

Research Field
Physics
Education Level
PhD or equivalent

Languages
FRENCH
Level
Basic

Research Field
Chemistry » Physical chemistry
Years of Research Experience
1 – 4

Research Field
Physics » Chemical physics
Years of Research Experience
1 – 4

Research Field
Physics » Biophysics
Years of Research Experience
1 – 4

Additional Information
Eligibility criteria

Applicants should hold a PhD in Organic Polymer Chemistry with solid expertise in techniques from the synthesis to the characterization. Specific knowledge in electrochemistry conducting polymers is highly desired. Team capability and good skills in English are required.

Website for additional job details
https://emploi.cnrs.fr/Offres/CDD/UMR5629-ERICLO-002/Default.aspx

Work Location(s)

Number of offers available
1
Company/Institute
Laboratoire de chimie des polymères organiques
Country
France
City
PESSAC
Geofield

Where to apply

Website
https://emploi.cnrs.fr/Candidat/Offre/UMR5629-ERICLO-002/Candidater.aspx

Contact

City
PESSAC
Website
http://www.lcpo.fr

STATUS: EXPIRED

View or Apply
To help us track our recruitment effort, please indicate in your cover//motivation letter where (vacanciesin.eu) you saw this job posting.

Job Location