Postdoc in synthetic biology – DTU Biosustain

Job title:

Postdoc in synthetic biology – DTU Biosustain

Company:

Danmarks Tekniske Universitet

Job description

Job Category: VIP BJob Description:If you are establishing your career as scientist and you are looking for the best possible foundation for fulfilling your dreams and ambitions, it is right here in front of you. At DTU Biosustain you will break new ground at the absolute forefront of what is possible, focusing on expression of complex disulfide-containing proteins. In this position, you will develop tools for optimizing synthetic biology tools for expression of complex heterologous peptides and proteins.Responsibilities and qualifications
Your overall focus will be to strengthen the department’s competencies within expression of challenging proteins and peptides containing disulfide bridges. You will work with a team of leading scientist from both academically and industrial partners.Your primary tasks will be to:

• Develop synthetic biology tools for optimizing expression of disulfide-bridge containing peptides and proteins in bacterial host organisms.
• Develop tools for monitoring and optimizing correct folding of such proteins.
• Carry out expression and purification for functional characterization of selected proteins.
• Teach and supervise BSc and MSc student projects
• Potentially Co-supervise PhD students

As a formal qualification, you must hold a PhD degree (or equivalent). Moreover, having experience in the following will be beneficial: “Expression of disulfide-containing proteins and peptides in bacteria, including E. coli.

• Experience with investigating protein folding of complex proteins.
• Development of synthetic biology tools for modularizing genetic elements to facilitate efficient cloning and genetic reconstruction.
• Experience with working and handling non-model bacterial expression organisms, including thermophilic bacteria.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.The period of employment is 2.5 years (30 months) with an expected start date of June 1st (or according to mutual agreement). The position is a full-time position.You can read more about .Further information
Further information may be obtained from Professor Alex Toftgaard Nielsen (atn@biosustain.dtu.dk).You can read more about DTU Biosustain atIf you are applying from abroad, you may find useful information on working in Denmark and at DTU at .Application procedure
Your complete online application must be submitted no later than 27 May 2025 (23:59 Danish time).Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

• Application (cover letter)
• CV
• Academic Diplomas (MSc/PhD – in English)
• List of publications

Applications received after the deadline will not be considered.All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position.The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain)
Recent progress in our ability to read and write genomic code, combined with advances in automation, analytics and data science, has fundamentally changed the scope and ambition of harnessing the potential of biological systems. Big data approaches and analysis of biological systems are key research instruments at the Center. DTU Biosustain utilizes these advances for microbial cell factory design to foster sustainable lifestyles in relation to three application areas: Sustainable Chemicals, Natural Products, and Microbial Foods.Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

Expected salary

Location

Kongens Lyngby, Hovedstaden – Lyngby, Midtjylland

Job date

Wed, 14 May 2025 22:19:19 GMT

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