Postdoc in the Regulation of Skeletal Muscle Metabolism

Job title:

Postdoc in the Regulation of Skeletal Muscle Metabolism

Company:

Ku – Sund – Panum Kbh N

Job description

The University of Copenhagen is seeking an experienced Postdoc fellow to commence on June 1, 2025, or after agreement, for the Zierath Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen.About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) is an academic research Center that pioneers groundbreaking research towards better cardiometabolic health. Through collaborative interdisciplinary research from single-cell genomics to whole-body systems, CBMR aims to transform the basic understanding of cardiometabolic health and accelerate its translation into prevention and treatment strategies. The Center’s uniquely multi- and interdisciplinary approach combines research in genetics, physiology and pharma¬cology, to better understand the complex interplay of the many factors that drive cardiometabolic disease. You can learn more in the Executive Summary of CBMR’s Strategy 2024–2028.
CBMR was established in 2010 at the Faculty of Health & Medical Sciences and has been located in the Maersk Tower at Panum building since 2017. The around 260 employees create an international, highly collaborative research environment across disciplines.Our Research
The Zierath Group investigates the interactions between intrinsic biorhythms and external perturbations such as exercise and nutrient provision to identify novel translational strategies for prevention and treatment of metabolic diseases.Job Description
The project aims to understand how insulin and exercise regulate skeletal muscle remodeling and energy metabolism. The goal is to identify key enzymatic regulators of glucose metabolism and protein turnover that become dysregulated in insulin resistance. Using multi-omics analyses on human tissue, functional genomic screens in muscle cells, and skeletal muscle-specific knockout mouse models, the study will explore target mechanisms and their physiological roles. Additionally, potential circadian influences on insulin and exercise responses may be examined. Findings will deepen our understanding of muscle health and identify therapeutic targets.Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:Required qualifications:

• PhD in Physiology, Biology, Biochemistry, Molecular Biology, Molecular biomedicine, or a related field.
• Excellent scientific track record (i.e., publications, training) in relation to career stage.
• Skilled in applying various cell biology and biochemistry techniques to assess metabolism, cellular signaling, and mechanisms of action.
• Experience in identifying potential therapeutic targets through the generation and integration of multi-omics datasets.
• Strong expertise in studying metabolism and insulin signaling at both the whole-body and cellular levels using cell and mouse models, as well as human datasets.
• Having a FELASA or equivalent certification for animal experimentation is desirable.
• Proficiency in conducting high-throughput functional screens in vitro, including CRISPR technology.
• Excellent English communication skills both written and verbal, with the ability to effectively interpret and present results in a physiological context

Terms of Employment
The employment as Postdoc is a full-time position for 2 years. The starting date is June 1, 2025, or after agreement.
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.Non-Danish and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark for the past 10 years.The position is covered by the Job Structure for Academic Staff at Universities 2020.Questions
For further information about the position, please contact Professor Juleen R. Zierath at juleen.zierath@sund.ku.dk. For questions regarding the recruitment procedure, please contact HR at sund-hr-cbmr@sund.ku.dk.The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark.Application Procedure
Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:

• Cover letter expressing the motivation and previous research experience of the applicant (max. one page)
• Curriculum vitae
• Copy of the PhD degree certificate and the Master’s degree certificate.
• List of publications
• References (name and contact details of at least two references)

Application Deadline: 11 March 2025, 23.59pm CETWe reserve the right not to consider material received after the deadline and not to consider applications that do not live up to the abovementioned requirements.The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.The applicant will be assessed according to Ministerial Order No. 242 of March 13, 2012, on the Appointment of Academic Staff at Universities.The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal backgrounds.

Expected salary

Location

København

Job date

Thu, 27 Feb 2025 23:57:53 GMT

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