Postdoctoral fellow – GE32 – Department of Diagnostic Sciences
Offer DescriptionLast application date: Jan 31, 2025 00:00Department: GE32 – Department of Diagnostic SciencesContract: Limited durationDegree: PhD in Biology, (Bio)medical Sciences, Biotechnology, Bioinformatics or equivalentOccupancy rate: 100%Vacancy type: Research staffJob descriptionThe research group of Prof Tom Taghon at Ghent University in Belgium ( ) is looking for a motivated postdoctoral researcher with an interest in T cell development and single cell genomics to join the team. We are a dynamic and international lab with a focus on the functional characterization of the molecular mechanisms that control human T cell development (Liang et al. Nat Immunol 2023, Lavaert et al. Immunity 2020; Roels et al. Nat Immunol 2020). As part of the Human Cell Atlas Thymus Seed Network, we have also been involved in high-resolution profiling of the developing human thymus using single cell multiomics and spatial transcriptomics (Yayon et al. Nature 2024, Park et al. Science 2020).The Project:
γδ T cells are an unconventional lymphocyte subtype that fundamentally differs from conventional αβ T cells in their antigen-recognition, MHC dependence and effector functions. Like all T cells, γδ T cells develop in thymus but especially in human the molecular mechanisms of this process are not fully understood. The postdoc will be part of a concerted effort to unravel the details of human γδ T cell differentiation before and after birth using state-of-the-art technologies, such as CRISPR/Cas9, flow cytometry and in vitro organoid cultures. A key component of the project will be multimodal single cell data (CITE-seq, scATAC-seq) and spatial transcriptomics, thus a keen interest in learning single cell/spatial data analysis is critical. The project is linked to a collaboration with the lab of David Vermijlen (ULB, Belgium), who are experts in the field of prenatal γδ T cell development and effector programming.Job profile
What we offer:
How to applyFor further information or to apply (include motivation letter, curriculum vitae and contact information of three potential referees), please contact Prof. Dr. Tom Taghon ( ).
The evaluation of the applicants starts in January 2025 and continues until the position is filled. Preselected candidates will be invited for an (online) interview. Starting date will be determined in agreement with the selected candidate.Where to apply WebsiteRequirementsResearch Field Biological sciences Years of Research Experience 4 – 10Research Field Technology Years of Research Experience 4 – 10Additional InformationWebsite for additional job detailsWork Location(s)Number of offers available 1 Company/Institute Ghent University Country Belgium City Ghent Postal Code 9000 Street Sint-Pietersnieuwstraat 33Contact CityGhent WebsitePostal Code9000STATUS: EXPIREDShare this page
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Sun, 22 Dec 2024 08:16:01 GMT
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