Postdoctoral Research Fellow

Job title:

Postdoctoral Research Fellow

Company:

University of Edinburgh

Job description

Job Category: AcademicJob Description:Grade UE07: £40,497 to £48,149 per annumCMVM/Clinical Sciences/Institute for Regeneration and Repair/Centre for Reproductive HealthFull-time: 35 hours per weekFixed-term: for 3 yearsThe Opportunity:This job post is for a postdoctoral research associate to conduct research on the role of two G-coupled receptors in the progression of difficult-to-treat acute myeloid leukaemia (AML).The job holder will need to (i) study the biology of GPR56/GPR97 in leukemic cells (and in normal haematopoietic stem cells as a control), (ii) establish leukaemia cell lines and human iPSCs lacking one or both GPRs, and (iii) study their effects on haematopoietic cell function to identify mechanisms involved in AML progression and chemo-resistance.This post is full-time (35 hours per week).Any appointment above spine point 4 (i.e. UE07/35) on the scale may result in a reduced contract length than advertised due to budget restraint.The salary for this post is £40,497 to £48,149 per annum.Your skills and attributes for success:

• Appropriate degree, with relevant post-graduate research experience and accumulated knowledge.
• A PhD or equivalent professional qualification and/or experience in the field of normal and malignant haematopoiesis.
• PhD (or to be completed within 2 months of interview date) in an appropriate field.
• Experience on cell culture (human primary cells, cell lines and human iPSCs).
• Strong expertise in multi-colour flow cytometry, CRISPR/Cas9 and molecular biology.

Click to view a copy of the full (opens new browser tab).Application InformationInsert any specific details about the application process and documents that may be required, for example:Please ensure you include the following documents in your application:– CV– Cover letterAs a valued member of our team you can expect:

• A competitive salary.
• An exciting, positive, creative, challenging and rewarding place to work.
• To be part of a diverse and vibrant international community.
• Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our

(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.Championing equality, diversity and inclusionThe University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab).The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa.Key dates to noteThe closing date for applications is 20 June 2025.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.Interviews will be held in the first week of July.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Centre for Reproductive Health (CRH; Director; Professor Andrew Horne) at the University of Edinburgh has the largest concentration in the UK of scientists who study reproductive health, from basic biology to clinical translation. It is one of the leading Centres in reproductive health in the world and is a trusted source for this research globally.CRH conducts fundamental and applied research that aims to develop novel treatments for the major unmet needs in reproductive disorders and to exploit impacts of this research across medicine. The internationally competitive research activity of reproductive scientists based within the Centre is augmented by clinical activities based within the adjacent Royal Infirmary and Simpson Centre for Reproductive Health.A central mission is “to gain fundamental understanding of the impact of reproductive processes and their pathologies on the entire life-span of males and females: to use this knowledge to improve human health from birth to old age and to provide leadership in training and public engagement in reproductive health“. This vision is currently enabled by four groupings: (i) Reproductive Resilience, Proliferation, Differentiation and Repair (ii) Reproductive system cancers: aetiology, pathogenesis and therapy (iii) Optimizing life-long health through pregnancy and perinatal interventions (iv) Immune-Endocrine interactions in Reproductive Health.

Expected salary

£40497 – 48149 per year

Location

Edinburgh – Midlothian

Job date

Fri, 23 May 2025 04:27:37 GMT

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