Postdoctoral Researcher in RNA 3D structure modeling
Laboratory of Bioinformatics and Protein Engineering at the International Institute of Molecular and Cell Biology (IIMCB), Warsaw, headed by Prof. Janusz M. Bujnicki, offers a position for aPostdoctoral Researcherin RNA 3D structure modelingDeadline for applications: September 15th, 2025. Preferred job starting date: October 1st, 2025 or as soon as possible.As a Postdoctoral Researcher, you will be involved in interdisciplinary analyses of RNA structure focused on mechanistic, structure-level understanding of how posttranscriptional modifications influence RNA folding and its ability to form alternative 3D structures.This position is ideal for you if you have solid experience in bioinformatics and computational biology, in particular in simulations of RNA folding in 3D using coarse-grained models, Monte Carlo sampling and statistical potentials. We are also interested in applications from candidates with experience in software development, who can contribute to be our interdisciplinary work on RNA structure.Our laboratory studies the structures and mechanisms of biological macromolecules, in particular RNA and macromolecular complexes involving nucleic acids, proteins, and small molecules. We use experimental approaches such as chemical probing, crystallography, cryo-EM, circular dichroism, and SAXS to characterize the structures and functions of RNAs and their complexes. We also develop and use computer programs for data analyses, in particular for modeling based on experimental data.The Institute is equipped with state-of-the-art technology, has excellent core facilities and supportive administration. IIMCB benefits from numerous generous funding schemes for basic research through grants from international and national sources. The institute is located in a large biomedical campus that offers access to equipment and various possibilities of training and collaboration. We provide opportunities for interdisciplinary collaborations. The working language of the institute is English.We offer:
We require:
2. computational simulations of RNA and protein structure and dynamics, 3. programming in C/C++ and Python, and 4. development of potentials for scoring inter- and intra-molecular interactions in molecular models
Selection criteria:Applications will be evaluated based on the following criteria: * Education and formal qualifications.
o Clarity and impact of motivation letter.o Communication and teamwork abilities.o Organizational and time-management skills.o Compatibility with the research group’s goals and vision.How to apply:
The Postdoctoral Researcher will be selected from candidates in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy . The competition may be extended or repeated until suitable candidates who fulfill all requirements are found.This position is offered within a project entitled “Unraveling the influence of posttranscriptional modifications on RNA 3D structure formation and its dynamics, with the integrated use of theoretical and experimental approaches” carried out as the OPUS grant of the Polish National Science Centre (UMO-2020/37/B/NZ2/02456).
Warszawa, mazowieckie
Fri, 22 Aug 2025 07:33:15 GMT
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