Postdoctoral Researcher (Preclinical Tumour Biologist and Imaging specialist)
Offer DescriptionTitle: Postdoctoral Researcher (Preclinical Tumour Biologist and Imaging specialist)Salary: Aligned with IUA Research salary scale, up to a maximum starting salary of PD1 Point 5 (€47,854 per annum) depending on experience.Department: Physiology and Medical PhysicsTenure: Specified purpose contract for 18 monthsLocation: RCSI St. Stephens Green Campus, Dublin City CentreReporting to: Professor Annette Byrne, Head, RCSI Precision Cancer Medicine GroupRequired Start Date: June 1st 2024About RCSIRCSI is a community of academic, research, clinical and professional staff working collaboratively to lead the world to better health. Here, you will thrive in an innovative and inclusive atmosphere and your personal development and wellbeing will be supported. We invite you to join us to help deliver on our exciting mission “To educate, nurture and discover for the benefit of human health”. We seek candidates whose experience to date has prepared them to contribute to our commitment to the at RCSI. Our students come from all walks of life and so do we. We hire great people from a wide variety of backgrounds. This makes our university stronger and ensures we hire the best talent.For each of the last six years, RCSI has been positioned in the Top 300 of universities worldwide in the Times Higher World university Rankings. We are proud to announce that RCSI has ranked first in the world for “Good Health and Well-being” in the Impact Rankings 2023. This reflects our commitment to supporting people of all ages to live healthy lives and our work to promote the concepts of well-being and positive health. Our values of Respect, Collaboration, Scholarship and Innovation continue to unite and direct our purpose.About Our Researchrecognises that excellence in research is critical to the quality of its educational activities, its credibility, and, overall, to its mission to enhance human health. RCSI’s research strategy aims to build upon its strength in translational biomedical and clinical research to deliver transformational, high impact changes in health care. Targeting both Irish national and funding, along with increased collaboration with industry, is a major part of the RCSI research strategy. Forging increased collaboration between RCSI and industry is of critical importance to achieving success in this area. RCSI is also committed to provide its researchers with the supports and developmental opportunities to enable them to continuously grow and support their overall career development.The led by , is located in the RCSI .The PCM Group focuses on the development of novel precision medicine approaches in the oncology setting and works to elucidate novel predictive biomarkers (genomic, transcriptomic, proteomic, imaging) and to identify new therapeutic targets. The overall goal is to improve patient outcomes with a particular focus on colorectal and brain malignancies. To achieve our objectives, we employ highly disruptive and innovative approaches including multi-modality molecular imaging, state-of-the-art preclinical models and Next Generation Sequencing (NGS) of clinical samples, having access to oncology patient data sets.Professor Byrne has extensive expertise in coordinating and collaborating in large European research projects funded by the European Union ( ; ; ), as well as leading several national programmes funded by Science Foundation Ireland (SFI), the Irish Heath Research Board (HRB) and others.Open PositionWe are seeking to recruit a post-doctoral tumour biologist (preclinical) to join the PCM Group. The successful appointee will work primarily on a SFI funded programme entitled “Leveraging chromosomal instability for improved diagnosis and treatment in bevacizumab resistant metastatic colorectal cancer”, where their main role will be to lead preclinical validation imaging studies.Project DescriptionThe project builds on previous high impact publications (Nat Commun. 2018 Oct 5;9(1):4112 & J Clin Oncol. 2018 Jul 10;36(20):2052-2060) that have identified a new classification system (based on copy number alterations patterns) to predict patient response to chemotherapy + bevacizumab (BVZ) in RAS mutant metastatic colorectal cancer (mCRC) patients. Overall, we seek to understand why tumours displaying high CIN respond to BVZ and unravel the underlying biology that drives this response.Job descriptionThe successful candidate will be responsible for the preclinical imaging studies due to start on the project during 2024. Specifically, they will evaluate the impact of BVZ + standard of care chemotherapy on cancer hallmarks across CIN subtypes in preclinical models employing multi-modality imaging studies. Overall, the study will further unravel the underlying biology that drives BVZ response in this disease.Key tasks
, ICR) and Belgium ( (VIB KU-Leuven) to analyse the preclinical study results in the overall context of the projectThe candidate will be expected to:
Qualifications – (Essential)
Knowledge, Skills & Experience – (Essential)
Knowledge, Skills & Experience – (Desirable)
Standard requirements of all positions
Employee BenefitsRCSI make sure you have the resources you need to thrive by offering a wide range of benefits in areas including time away, finance, community, health, and well-being and insuring your financial future. Below are some additional benefits available to you as an RCSI employee:
Application ProcessPlease email with informal inquiries.Please apply online at with your covering Letter and CV containing contact details of 2 references no later than 5pm on the closing date (2nd May 2024).We are all too aware that imposter syndrome and the confidence gap can sometimes stop fantastic candidates putting themselves forward, so please do apply – we’d love to hear from you.Please Note:This job description may be subject to change to reflect the evolving requirements of the Department and RCSI in developing healthcare leaders who make a difference worldwide.Similar vacancies that arise in the next 6 months maybe filled from the pool of applicants that apply for this position.RCSI is proud to be an equal opportunity employer and welcome applications from all suitably qualified persons regardless of their gender, civil status, family status, sexual orientation, religion, age, disability or race.If you have any particular requirements for your interview, please notify the Human Resources Department at your earliest convenience.Employees are required to undertake 6 months service in their current role before applying for other internal opportunities, unless agreed in advance by the SMT representative.RequirementsResearch Field All Education Level PhD or equivalentAdditional InformationWork Location(s)Number of offers available 1 Company/Institute Royal College of Surgeons in Ireland Country Ireland GeofieldWhere to apply WebsiteContact State/ProvinceDublin CityDublin 2 WebsiteStreet123 St Stephen’s Green Postal CodeCo.Dublin E-Mailrebeccaobrien@rcsi.ie Phone0877558652STATUS: EXPIRED
€47854 per year
Dublin
Fri, 29 Mar 2024 03:49:26 GMT
To help us track our recruitment effort, please indicate in your email/cover letter where (vacanciesin.eu) you saw this job posting.
vacanciesin.eu Job Description Dans le cadre de votre apprentissage, vous aurez pour missions de :…
vacanciesin.eu Job Description Rattaché-e au service RH du site de Caudebec-Lès-Elbeuf composé de 6 personnes…
vacanciesin.eu Job Description Le stagiaire sera intégré à l'équipe Supply Chain d'AGI. Son objectif 1er…
vacanciesin.eu DESCRIPTION Chez Amazon nous considérons que chaque jour dans l'entreprise est aussi important que…
vacanciesin.eu Job Description Dans le cadre d'une croissance des activités de Safran Electronics & Defense,…
vacanciesin.eu Job Description Le site de Safran Aircraft Engines Chatellerault compte près de 1000 personnes…