Doctoral Candidate

Job title:

Doctoral Candidate

Company:

Straumann Group

Job description

This PhD position is part of the European Doctoral Network “SHIELD” (Strategies for Healing Implant-associated infections and Enhancing Longevity in Devices). SHIELD offers an exciting opportunity for 16 early-career researchers to contribute to transforming the management of infections associated to medical implants. Focused on addressing the challenges posed by implant-associated infections (IAIs), SHIELD aims to deepen our understanding of IAI mechanisms and develop innovative antibacterial biomaterials to improve patient outcomes.Join the prestigious Marie Skłodowska-Curie Actions Doctoral Network SHIELD (Strategies for Healing Implant-associated infections and Enhancing Longevity in Devices) and contribute to cutting-edge research aimed at combating implant-associated infections.ObjectivesThis PhD project aims to prepare and characterize nanostructured biofilm-repellent surfaces on titanium implants, to evaluate the clinical performance of biomimetic and personalized macroscopic designs for soft-tissue healing using in vitro models of bacterial adhesion and fibroblast proliferation in collaboration with University of Gothenburg and in-vitro dental polymicrobial biofilm model in collaboration with University of Oslo, and, finally, to evaluate these approaches using in vivo models through rigorous animal and/or clinical studies in collaboration with Hospices Civils de Lyon.Research activities include:

• Characterization of nanostructured surfaces
• Simulating biofilm model/host interactions via a flow cell co-culture system with bacterias and fibroblasts
• Assessing the effectiveness of customised, anatomically shaped devices using in vitro and/or animal models
• Develop and conduct an interventional study protocol on patients to compare the most effective nanostructured surface with a polished reference surface at individual implant sites.

Training and mobility:

• Research secondments at SHIELD partner institutions:

-University of Gothenburg (Sweden)-University of Oslo (Norway)– Hospices Civils de Lyon (France)

• Participation in specialised training workshops and international conferences.

Required Education Level

• Research Field: Medical sciences and Dentistry
• Education Level: Master’s degree or equivalent

Skills/Qualifications/Specific requirements:

• Applicants must have completed a dentistry training (DDS) with a first experience in research
• Alternatively, applicants should hold a Master’s degree or equivalent in microbiology, biotechnology or medical sciences or similar providing access to PhD programs and should have experience with experimental research and dentistry/implantology
• Applicants must have excellent proficiency in written and spoken English
• Applicants must have a good French language level (B2 level minimum)
• Strong motivation and ability to collaborate in an interdisciplinary and international team

Background information on all DC positions and the SHIELD Doctoral Network is available on:––

Expected salary

Location

Sallanches, Haute-Savoie

Job date

Sun, 24 Aug 2025 07:01:55 GMT

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