Job title:
Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences
Company:
Job description
Offer DescriptionProject Description:
Chronic wounds affect 4 million Europeans annually, with approximately 1% of individuals in highly developed countries experiencing this problem. Existing therapies are expensive and around 2-4% of European healthcare budget are allocated to wound treatment. Despite relative success in therapy, serious complications occur in approximately 10% of cases, rising to 30% in patients with diabetes or immunocompromised patients. It has been reported that in 10% to 20% of infected wounds Methicillin-resistant Staphylococcus aureus (MRSA) is found that makes wound management even more challenging. Chronic, non-healing wounds often require prolonged hospitalization, multiple surgeries and can lead to leg amputation. Therefore, the ideal wound dressing should provide a complex treatment that counteract skin infections and promotes regeneration of tissue with impaired blood supply. The aim of AntiMicroMXen project is to develop a new generation of electrospun wound dressings made from polycaprolactone (PCL), polylactic acid (PLC) and gelatine, integrated with bacteriophages against S. aureus, antibacterial, hemostatic and reactive oxygen scavenging ability of MXenes and pro-regenerative factors derived from immortalized Human Adipose Tissue Mesenchymal Stem Cell (HATMSC) cells. Regenerative factors produced by HATMSC cells, known as the secretome, have shown beneficial effects in wound healing. The secretome of this cell line exhibits strong pro-proliferative and pro-angiogenic activity. Moreover, a highly efficient method for producing these factors has been developed at IITD PAN.
We offer : postdoctoral researcher possitionPlanned start date: From July 1, 2025
Employment duration: 18 monthsWhere to apply E-mailhonorata.kraskiewicz@hirszfeld.plRequirementsResearch Field Biological sciences Education Level PhD or equivalentSkills/Qualifications
- A PhD in biological, medical, or related sciences obtained in the year of employment or within 7 years before January 1st of the year of employment
- Strong motivation for research work, scientific curiosity, and willingness to collaborate
- Experience and knowledge in regenerative medicine, chronic wound treatment, or biomaterials used in regenerative medicine is welcome (but not mandatory)
- Experience with cell culture, molecular biology techniques (RT-PCR, Western blot), ELISA, and immunocytochemistry
- Strong communication skills and practical knowledge of English
- Ability to read scientific literature and write scientific publications
- Scientific achievements confirmed by publications
- International experience will be an additional asset
Specific RequirementsScope of Responsibilities:
- Performing research tasks aimed at developing a dressing that releases active factors derived from HATMSC cells
- Designing and performing biocompatibility tests of electrospun membranes, seeding cells on biomaterials, and visualizing cells on tested membranes
- Designing and conducting in vitro functional tests
- Data analysis and interpretation
- Writing reports and scientific publications
- Supervising interns/trainees/students
Languages ENGLISH Level ExcellentResearch Field Biological sciencesAdditional InformationSelection processTerms of Employment:The selected candidate will receive a salary under an employment contract in accordance with NCN regulations: “Terms and Regulations for Granting Funds for Tasks Financed or Co-Financed in International Competitions Organized by the National Science Centre under Multilateral Cooperation UNISONO” (Annex to NCN Council Resolution No. 28/2022 of March 2, 2022).Planned start date: From July 1, 2025
Employment duration: 18 monthsRequired Documents:
- Motivation letter describing interests and scientific achievements
- CV
- Copy of diploma
For more information, please contact Dr. Honorata Kraśkiewicz (email: , phone: +48 71 370 9913).
Applications containing all required documents should be sent by June 20, 2025, by 10:00 AM, via email to the project leader, Dr. Honorata Kraśkiewicz (email: ).The successful candidate will be selected through a competition in accordance with NCN and internal institutional regulations. The decision will be announced by June 27, 2025. The planned start date for employment in the project is July 1, 2025.
The Committee reserves the right not to select any candidate. In such a case, the competition will be re-announced. Detailed employment conditions will follow the internal regulations of the institute and be defined in a contract between the candidate and the Director of IITD PAN in Wrocław.Additional Information:The fellow will be selected by a Recruitment Committee chaired by the Project Leader. The Committee reserves the right to invite selected candidates for an interview.Terms of Employment:
The selected candidate will receive a salary under an employment contract in accordance with NCN regulations: “Terms and Regulations for Granting Funds for Tasks Financed or Co-Financed in International Competitions Organized by the National Science Centre under Multilateral Cooperation UNISONO” (Annex to NCN Council Resolution No. 28/2022 of March 2, 2022).
Planned start date: From July 1, 2025
Employment duration: 18 monthsAdditional commentsPlease include in your application: “I hereby give my consent for my personal data included in my application to be processed by the Hirszfeld Institute Of Immunology and Experimental Therapy. Polish Academy of Sciences for the purposes of the recruitment process (in accordance with Article 6(1) of Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016).”Work Location(s)Number of offers available 1 Company/Institute Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences Country Poland State/Province Lower Silesia City Wrocław Postal Code 53-114 Street Rudolfa Weigla 12Contact CityWrocław WebsiteStreetRudolfa Weigla 12 Postal Code53-114 E-Mailkatarzyna.kogut@iitd.pl Phone713709930STATUS: EXPIREDShare this page
Expected salary
Location
Wrocław, dolnośląskie
Job date
Tue, 13 May 2025 23:13:08 GMT
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