Job title:
PhD Student – Department of Biomolecular Medicine
Company:
Job description
Offer DescriptionLast application date Jun 01, 2024 00:00Department GE31 – Department of Biomolecular MedicineContract Limited durationDegree Master’s degree in Medicine, Biomedical Sciences, Biotechnology, Bioengineering, Pharmaceutical sciences, or equivalentOccupancy rate 100%Vacancy type Research staffJob descriptionLong-Read Sequencing for the detection of cryptic Structural Variation in patients with intellectual disability and congenital anomaliesThe Genome Research group at the Center for Medical Genetics has a longstanding expertise in the introduction of new technologies in the elucidation of genomic defects in children with congenital anomalies. Our research group is currently implementing third generation sequencing (long-read sequencing) for the detection of hidden structural variations in the genome of these patients, and we are looking for a talented and highly motivated PhD student to enforce our team.We offer an open, highly dynamic, and challenging working environment, in which teamwork, initiative and originality are stimulated and appreciated.
Tasks:
o Experimental Design and Execution:
Implement long-read sequencing protocols using PromethION and Revio platforms.
Prepare and process genomic DNA samples for sequencing.
o Data Analysis:
Analyze long-read sequencing data to identify structural variations, including deletions, duplications, inversions, and translocations.
Develop methods for tandem repeat detection and characterization.
Investigate epigenetic signatures associated with specific genomic regions.Job profileQualifications:
- Strong interest in genome research and next-generation sequencing technologies.
- Experience with long-read sequencing platforms (PromethION, Revio) is advantageous.
Bioinformatics Skills:
- Proficiency in Python and R for data analysis, visualization, and statistical modeling.
- Experience with bioinformatics tools commonly used in genome research (e.g., SAMtools, BCFtools, BEDtools, GATK, Dorado, Minimap2, etc.).
- Ability to work with large-scale genomic datasets and perform variant calling.
- You take initiative, have a critical mindset, strive to work independently and are highly motivated.
- Excellent written and oral communication skills
- Collaborate with other researchers, bioinformaticians, and clinicians within the hospital.
- Participate in lab meetings, seminars, and scientific discussions.
- Fluency in English (both written and spoken).
- Candidates who are eligible to submit a PhD research project to other funding agencies, will be considered as an advantage.
What we can offer
- We offer a full-time position as a doctoral fellow, consisting of an initial period of 12 months, which will be extended (after a positive evaluation), to a total maximum of 48 months.
- Your contract will start on 06/01/2024 at the earliest.
- The fellowship amount is 100% of the net salary of an AAP member in equal family circumstances. The individual fellowship amount is determined by the Department of Personnel and Organization based on family status and seniority. A grant that meets the conditions and criteria of the regulations for doctoral fellowships is considered free of personal income tax.
- All Ghent University staff members enjoy a number of benefits, such as a wide range of training and education opportunities, 36 days of holiday leave (on an annual basis for a full-time job) supplemented by annual fixed bridge days, bicycle allowance and eco vouchers.
(in Dutch).How to apply
- Applications should be submitted by June 1, 2024.
- Send a motivation letter and curriculum vitae with detailed study results (per year) to Prof. Dr. Björn Menten (Email:
) * Please also include extracurricular activities and the contact information of two references.RequirementsResearch Field Biological sciences Years of Research Experience 1 – 4Research Field Biological sciences Years of Research Experience 1 – 4Research Field Chemistry Years of Research Experience 1 – 4Research Field Engineering Years of Research Experience 1 – 4Research Field Engineering Years of Research Experience 1 – 4Research Field Medical sciences Years of Research Experience 1 – 4Research Field Pharmacological sciences Years of Research Experience 1 – 4Research Field Technology Years of Research Experience 1 – 4Additional InformationWebsite for additional job detailsWork Location(s)Number of offers available 1 Company/Institute Ghent University Country Belgium City Ghent Postal Code 9000 Street Sint-Pietersnieuwstraat 33Where to apply WebsiteContact CityGhent WebsitePostal Code9000STATUS: EXPIRED
Expected salary
Location
Gand, Flandre-Orientale
Job date
Fri, 26 Apr 2024 06:25:29 GMT
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