PhD: studying neurodegeneration using iPSC and xenotransplantation models

Job title:

PhD: studying neurodegeneration using iPSC and xenotransplantation models

Company:

Job description

Offer DescriptionParkinson’s disease and multiple system atrophy belong to a broader family of brain disorders characterized by glial and neurodegenerative pathologies. The exact etiology of these diseases remains unclear, but recent studies suggest that oligodendroglial cells may be early contributors to the disease process of these brain disorders.As a PhD student, you will be responsible for developing innovative oligodendroglial humanized cell and animal models. You will work with human induced pluripotent stem cells, which will be further transplanted into mouse models via xenotransplantation. This approach will enable the study of the role of human cells in Parkinson’s disease and multiple system atrophy.This project offers a unique opportunity to contribute to cutting-edge research on the causes and treatments of neurodegenerative disorders, while developing your own skills and expertise in a stimulating research environment.Keywords: Neurodegeneration, human pluripotent stem cells, xenotransplantation, alpha-synuclein, animal models, multiple system atrophy, Parkinson’s diseaseRequirementsResearch Field Biological sciences Education Level Master Degree or equivalentLanguages ENGLISH Level ExcellentResearch Field Biological sciences Years of Research Experience 1 – 4Additional InformationBenefits

• A full-time PhD position for 1 year, with the possibility of extension
• PhD training in the KUL doctoral school
• Work and collaborate with internationally leading multidisciplinary teams with relevant experience and expertise
• Support with the application for an FWO grant (applying for an FWO grant is a condition)
• If an FWO grant is not obtained, further funding will be considered
• Competitive salary

Eligibility criteria

• The candidate has a master’s degree in medicine, biomedical sciences, pharmaceutical sciences, biology, bioscience engineering, biochemical sciences or a related discipline.
• Experience with human induced pluripotent stem cells (iPSCs) is a plus
• Experience with animals is a plus
• Top 25 for grades obtained during Bachelor/Master
• The candidate is motivated to work with complex cell cultures and laboratory animal
• Excellent oral English communication and presentation skills are required
• Passion for research and sense of perseverance
• Critical mind with a great sense of initiative
• Good interpersonal skills
• Since the candidate must apply for a PhD scholarship, a master’s degree obtained in the European Union, the European Economic Area or Switzerland is a requirement.

Selection processFor more information please contact Prof. dr. Wouter Peelaerts, tel.: +32 16 37 40 59, mail: .
You can apply for this job no later than 02/05/2024 via theWork Location(s)Number of offers available 1 Company/Institute KU Leuven Country Belgium State/Province Vlaams Brabant City Leuven Postal Code 3000 Street Leuven GeofieldWhere to apply WebsiteContact State/ProvinceLeuven CityVlaams Brabant StreetLeuven Postal Code3000STATUS: EXPIRED

Expected salary

Location

Louvain, Brabant Flamand

Job date

Mon, 15 Apr 2024 01:50:21 GMT

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