POST DOC POSITION

Organisation/Company

INSERM U1112

Research Field

Biological sciences » Biology
Medical sciences
Computer science

Researcher Profile

First Stage Researcher (R1)
Recognised Researcher (R2)

Country

France

Application Deadline

14 May 2024 – 00:00 (UTC)

Type of Contract

Temporary

Job Status

Full-time

Is the job funded through the EU Research Framework Programme?

European Union / Next Generation EU

Is the Job related to staff position within a Research Infrastructure?

Yes

Offer Description

The research laboratory UMRS_1112 (INSERM and Université de Strasbourg) is looking for a highly motivated postdoctoral fellow to join our team on ciliopathies and ultra rare retinal degeneration syndromes.

Our Group is performing translational research in this field of rare diseases from gene identification and genomic analysis of modifiers to various cell line biomarkers and characterization, mouse modelling and overall pathogenesis mechanism understanding. We have gathered a unique biobank and a unique genomic dataset on this group of diseases.

This position comes with a European Project PREDICT generated by the European Joint Program on Rare Diseases (EJP-RD) and leans on studying in depth phenotype and genotype correlation of a selected set of ciliopathies.

The Post doc will have 2 missions:

• Contribute with our bioinformatics team and our collaborators to the analysis of whole genome sequencing data from a subset of patients with Bardet-Bield syndrome to identify modifiers
• Pursue the development of cellular and molecular characterization of various models of ciliopathies with RNA seq analysis especially by way of patients cells, iPSCs and eventually organoids, to identify molecular triggers especially for the retinal cells

The Institut de Génétique Médicale d’Alsace (IGMA) is located in the Centre de Recherche Biomédicale de Strasbourg (CRBS) offering an ideal setting for research in the field of rare disease and cellular biology as well as genomics. The vicinity of medical genetics clinical team, at the same floor, and our clinical reference centres is a great opportunity for translational projects at various levels.

REQUIRMENTS:

• PhD degree with a background in cell biology and strong background in bioinformatics especially genomics and RNA seq (dual training in biology and bioinformatics)
• Experimental skills, notably in cell culture
• The applicant should have excellent organizational skills, be highly motivated and wanting to integrate a multidisciplinary team with enthusiasm.

The position is available from May 2024. This initial funding for 24 months. Candidates are expected to have a competitive track record. Candidates should send their CV including research interests to [email protected]

Requirements

Research Field

Biological sciences » Biology

Education Level

PhD or equivalent

Research Field

Medical sciences

Education Level

PhD or equivalent

Research Field

Pharmacological sciences

Education Level

PhD or equivalent

Skills/Qualifications

PhD biology or/and computing (or preferred as mixed skills )

Specific Requirements

o PhD degree with a background in cell biology and strong background in bioinformatics especially genomics and RNA seq ( dual training in biology and bioinformatics )
o Experimental skills, notably in cell culture
o The applicant should have excellent organizational skills, be highly motivated and wanting to integrate a multidisciplinary team with enthusiasm.

Languages

ENGLISH

Level

Excellent

Research Field

Biological sciencesMedical sciences

Years of Research Experience

1 – 4

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

CRBS – INSERM

Country

European Union

City

STRASBOURG

Postal Code

67000

Geofield

Where to apply

E-mail

[email protected]

Contact

City

STRASBOURG

Website

https://www.u1112.inserm.fr/

Street

1 Rue Eugène Boeckel

Postal Code

67000

E-Mail

[email protected]

STATUS: EXPIRED