Post-doctoral Position in Organic Chemistry: Synthesis of lipid metabolite-inspired amphiphiles for the study of pharmaceutical relevant membrane proteins

Organisation/Company

Avignon Université

Research Field

Chemistry

Researcher Profile

First Stage Researcher (R1)

Country

France

Application Deadline

30 May 2024 – 22:00 (UTC)

Type of Contract

Temporary

Job Status

Full-time

Offer Starting Date

2 Sep 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The Post-doctoral fellow will be in charge of the chemical ligation between lipid-inspired hydrophobic domains prepared in the team of Montpelllier and glycosyl donors as well as their purification and complete structural characterization (1D and 2D NMR, MS-UPLC…). He/she will study the colloidal properties of the final amphiphiles by means of surface tension and spectrofluorometry measurements as well as dynamic light scattering. He/She will be working side by side with a PhD fellow. The biochemical validation will be carried out on several types of proteins of fundamental and pharmaceutical interest in Paris-Saclay and in Lyon.

Requirements
Specific Requirements

To apply to this position, you should have

Extensive and proven experience in organic synthesis.
Extensive and proven experience in characterization/purification of amphiphilic organic compounds.
High-level competency in investigating self-aggregation properties of amphiphiles.
Experience in biophysics and biochemistry of membrane proteins is helpful, but not essential.
Creativity in experimental design and effective team-working skills.
Excellent communication skills in French and English

Additional Information
Work Location(s)

Number of offers available

1

Company/Institute

Avignon Université

Country

France

City

Avignon

Geofield

Where to apply

Website

https://www.abg.asso.fr/fr/candidatOffres/show/id_offre/120661

Contact

Website

http://univ-avignon.fr/

STATUS: EXPIRED