Post-doctoral position – Research Engineer (14 months) : 3D printed / additive manufacturing calcium phosphate / hydroxyapatite biomaterials: Multiscale Porosity Bone Scaffold FreeForm

Job title:

Post-doctoral position – Research Engineer (14 months) : 3D printed / additive manufacturing calcium phosphate / hydroxyapatite biomaterials: Multiscale Porosity Bone Scaffold FreeForm

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Job description

Offer DescriptionPROJECT DESCRIPTION (MP-ScaFF abstract): The cranio-maxillo-facial bone diseases are growing rapidly in recent years, with around 1800 cases/year only due to osteonecrosis in France, as well as the number of accidental fractures requiring surgery. These diseases and traumas can cause critical size defects that are not self-repairable (
1 cm3). The advent and development in the Additive Manufacturing (AM) field allowed for rapid progresses in the production of customized scaffold lattices. However, it is still challenging to find a compromise in terms of good mechanical and biological performances, mainly due to the limitations of existing AM technologies in terms of pores geometries, resolution and dense wall thickness. The MP-ScaFF project focuses on the manufacturing of multiscale porosity and personalized calcium phosphate-based scaffolds through an innovative AM technology, the Dynamic Molding. This process, consisting of 3D printing an extrudable paste into a granular environment, allows for combining the advantages of AM processes as the freeform design for customized implants, and the advantages of the possibility to add sacrificial elements to generate microporosity. It will be possible not only to achieve a multi-scale porosity allowing to mimic the bone microstructure and promote cell proliferation, but also the addition of fully dense parts in the zones needing reinforcements as the screw fixings or external plates. The efficiency of this new implant will be tested in terms of both mechanical (by compression test) and biological (in vitro and in vivo behavior) performance. Furthermore, a simulation model will be developed to for an improved optimisation of scaffold design related to its mechanical behavior. The four partners of this project present the technical clinical skills and the complementarity needed to develop this innovative implant that addresses a public health problem.The recruited Postdoc fellow / Research engineer will work on two main axes:i) He/she will synthetize calcium phosphate raw materials specifically design for Dynamic Molding process (Material extrusion additive manufacturing).ii) He/she will perform microstructural, physico-chemical, and mechanical analysis of printed scaffolds, in order to improve the Dynamic Molding process to enhance final properties of the scaffolds (porosity size and orientation, mechanical properties, Calcium phosphate qualification…). With this aim, he/she will work with academic material scientist and 3Deus Dynamics Company ( ) who will provide Printed scaffold fabrication.Theses experimental work will be carried out at CIRIMAT laboratory where the Postdoc fellow / Research engineer will be hosted by the PPB group, (Phosphates, Pharmacotechnics, Biomaterials). ( )RequirementsResearch Field Engineering » Materials engineering Education Level Master Degree or equivalentResearch Field Chemistry » Inorganic chemistry Education Level Master Degree or equivalentSkills/QualificationsApplicants should have PhD degree (or alternatively Master Degree) in a relevant Materials Science discipline and basic skills on inorganic synthesis and the associated characterization methods: SEM, X-Ray, FTIR, AA, μtomography, mechanical tests, porometry, image analysis. Previous experience with calcium phosphate chemistry or biomaterials is much appreciated but is not strictly necessary.Languages ENGLISH Level GoodResearch Field Engineering » Materials engineeringChemistry » Inorganic chemistryEngineering » Biomaterial engineeringInternal Application form(s) neededPostDoc MP-ScaFF_CIRIMAT_FRANCE_0.pdfEnglish(220.29 KB – PDF)Additional InformationBenefitsSALARY: Postdoctoral / Research engineer position, Gross monthly salary: 2950 € euros (estimated)POSITION: 14 months (CIRIMAT) opening in September 1st, 2024 (Expecting start)Selection processStep 1: Application should be submitted before April 30th, 2024 by email with “Postdoc MP-ScaFF” as subject (Emails with other subjects will be rejected).Contact: D. GROSSINRequested enclosed documents:⦁ Filled Table of requested information (see in PDF or below).⦁ Full CV including degrees, certificates, accreditations and work experience.⦁ Certificate of Doctorate’s Degree.⦁ Recommendation letter(s) from previous supervisors or employers.⦁ List of publications.⦁ Copy of your ID/passport.Step 2: All applications will be reviewed by at least two members of the teamStep 3: The best candidates, based on their merit, will be shortlisted and invited for an interview. The interviews will be organised via a visioconference on May.Step 4: Shortlisted candidates will be ranked (or rejected).Step 5: Their applications will be submitted to the national security authority ( ) for validation.Step 6: The finally selected candidate will receive official notification.Step 7: Expecting start month september 2024.Internal Application form / TABLE OF REQUESTED INFORMATIONLast NameFirst NameMarried NameGenderType of ID or PassportNumberBirthdateCountry of BirthZip code and BirthplaceNationalityOther NationalityEmailCurrent Main AdressZip code and City CountryCurrent Professional SituationName of the current employing organizationAddress of employing organizationZip code and CityCountryWork Location(s)Number of offers available 1 Company/Institute CIRIMAT, ENSIACET, Toulouse-INP, CNRS Country France City Toulouse Postal Code 31400 Street 4 allée emile Monso GeofieldWhere to apply E-mail[email protected]Contact CityToulouse WebsiteStreet4 Allée Emile Monso Postal Code31030 E-Mail[email protected]STATUS: EXPIRED

Expected salary

€2950 per month

Location

Toulouse

Job date

Sat, 30 Mar 2024 04:39:55 GMT

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