Aarhus Universitet
Job title:
Postdoc in RNA-based therapeutics for viral targeting
Company:
Aarhus Universitet
Job description
The interdisciplinary Nanoscience center (iNANO) at Aarhus University invites applications for a 1-year postdoc position, with the possibility of extension. This position offers an exciting opportunity to join a research project focused on the in vitro selection of RNA-based therapeutics for targeting and inhibiting viruses, particularly Influenza A.The position is available from July 1st 2025 or as soon as possible hereafter.Expected start date and duration of employment This is a 1-year postdoc position, with the possibility of extension, starting from 1 July 2025 or as soon possible.Job description You are expected to contribute to a collaborative project focused on developing chemically modified RNAs targeting Influenza through in vitro selection (SELEX) methods. Binding and viral inhibition will be evaluated using biophysical techniques (such as SPR and BLI) and cell-based assays. Additionally, the structural determination of the complexes will be performed using cryo-Electron Microscopy (cryo-EM) in collaboration with structural biologists. This project is part of an international and interdisciplinary collaboration involving scientists in chemical biology, polymer chemistry, infectious diseases, and virology.Your profile Applicants should hold a PhD in molecular biology, biochemistry, nanoscience, nanotechnology, or medicinal chemistry and have experience with RNA and/or nucleic acid nanotechnology. Experience with aptamer selection, NGS sequencing, bioconjugation strategies, and binding/cell assays will be a major advantage. Experience with cryo-EM determination and bioinformatic pipelines will be an advantage.
The ideal candidate should be socially oriented, self-driven, and motivated, with strong communication skills and the ability to work as part of an international team. Proficiency in written and spoken English is a requirement for the position.Who we are iNANO, Interdisciplinary Nanoscience Center (www.inano.au.dk), was established in 2002 and at present is a major research and education center based at Aarhus University hosting 60 senior scientists, ~100 PostDocs and ~100 PhD students. The center combines expertise and faculty from Physics, Chemistry, Molecular biology and Medicine to carry out world-class interdisciplinary research in Nanoscience and Nanotechnology.The center gives access to a broad range of infrastructure, tools and expertise including clean-room facilities. With a 5-year undergraduate nanotechnology programme and nanoscience graduate programme (https://phd.nat.au.dk/programmes/nanoscience/) the center provides a full educational environment. In addition to the large base of basic research, the center has a large number of ongoing industrial projects and partnerships.In the Valero lab, we offer a dynamic, social and interdisciplinary scientific environment with a strong focus on nucleic acid chemistry, RNA technologies, biomedicine, and catalysis. Our team thrives in a collaborative atmosphere, working closely with leading scientists in biomedicine, virology, and synthetic biology at Aarhus University and within our international network.What we offer The centre offers:
- a well-developed research infrastructure, laboratories and access to shared equipment
- an exciting interdisciplinary environment with many national, international and industrial collaborators
- a research climate encouraging lively, open and critical discussion within and across different fields of research
- a work environment with close working relationships, networking and social activities
- a workplace characterised by professionalism, equality and a healthy work-life balance.
Place of work and area of employment The place of work is the Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C.Contact information Further information about the position may be obtained from Assistant Prof. Julián Valero and Prof. Jørgen Kjems, . Interested candidates are encouraged to contact for further details about the position.Deadline Applications must be received no later than 18 April 2025Application procedure Shortlisting is used. This means that after the deadline for applications – and with the assistance from the assessment committee chairman, and the appointment committee if necessary, – the head of department selects the candidates to be evaluated. All applicants will be notified whether or not their applications have been sent to an expert assessment committee for evaluation. The selected applicants will be informed about the composition of the committee, and each applicant is given the opportunity to comment on the part of the assessment that concerns him/her self. Once the recruitment process is completed a final letter of rejection is sent to the deselected applicants.Letter of reference If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline. Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.If you wish to add a referee after you have submitted your application, you must send this person’s details (name, job title, place of work, and email address) as well as the name of the position you have applied for to: [email protected]Formalities and salary range Natural Sciences refers to the .The application must be in English and include a curriculum vitae, degree certificate, a complete list of publications, a statement of future research plans and information about research activities, teaching portfolio and verified information on previous teaching experience (if any). Guidelines for applicants can be foundAppointment shall be in accordance with the collective labour agreement between the Danish Ministry of Taxation and the Danish Confederation of Professional Associations. Further information on qualification requirements and job content may be found in the .Salary depends on seniority as agreed between the Danish Ministry of Taxation and the Confederation of Professional Associations.Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.Research activities will be evaluated in relation to actual research time. Thus, we encourage applicants to specify periods of leave without research activities, in order to be able to subtract these periods from the span of the scientific career during the evaluation of scientific productivity.Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Read more . Please find more information about entering and working in Denmark .Aarhus University also offers a Junior Researcher Development Programme targeted at career development for postdocs at AU. You can read more about it .At the Faculty of Natural Science at Aarhus University, we strive to support our scientific staff in their career development. We focus on competency development and career clarification and want to make your opportunities transparent. On , you can find information on all types of scientific positions, as well as the entry criteria we use when assessing candidates. You can also read more about how we can assist you in your career planning and development.The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University’s website.Aarhus UniversityAarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 38,000 students (FTEs) and 8,300 employees, and has an annual revenues of EUR 935 million. Learn more at
Expected salary
Location
Aarhus, Midtjylland
Job date
Sat, 08 Mar 2025 06:44:25 GMT
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