Postdoctoral Researcher at the Center for Advanced Technologies

Job title:

Postdoctoral Researcher at the Center for Advanced Technologies

Company:

Job description

Offer DescriptionWe invite applications for a research position within the framework of a project funded by the National Science Centre (NCN) in Poland. The selected candidate will join an innovative research initiative focused on understanding the role of the HYL1 protein in the regulation of gene expression.About the Project:In eukaryotic cells, gene expression is tightly controlled at multiple stages, including chromatin accessibility, transcription, RNA processing, translation, and post-translational modifications. A key group of regulators in this process are microRNAs (miRNAs)-small, non-coding RNAs that direct gene silencing through sequence-specific interactions. The biogenesis of microRNAs is a complex, multi-step process that involves several protein factors. One of the central proteins in this pathway is HYL1, which binds double-stranded RNA and interacts with DCL1, the main RNase responsible for generating mature microRNAs from their precursors.HYL1 exists in two isoforms: phosphorylated and non-phosphorylated. While the phosphorylated form has traditionally been considered inactive in microRNA biogenesis, recent findings suggest it may play additional, previously unrecognized roles in the regulation of gene expression. In this NCN OPUS-funded project, we aim to explore how post-translational modifications of HYL1 influence its function and contribute to broader regulatory mechanisms within the cell.The research will involve the use of state-of-the-art molecular biology techniques, including:

• Immunoprecipitation and mass spectrometry to investigate protein-protein interactions and post-translational modifications
• Fluorescence imaging using confocal microscopy to study protein localization and dynamics
• Next-Generation Sequencing (NGS)for transcriptome and small RNA profiling

We Offer:

• Participation in a prestigious, NCN-funded research project
• Access to advanced research infrastructure at the Center for Advanced Technologies (CAT AMU) –
• Opportunity for professional development in a dynamic scientific team
• Engagement with cutting-edge techniques in molecular biology and genomics

Principal Investigator: Dr. Dawid BielewiczWhere to apply E-mail[email protected]RequirementsResearch Field Biological sciences » Biology Education Level PhD or equivalentSkills/QualificationsThe competition is open to individuals who meet the requirements specified in Article 113 of the Law on Higher Education and Science of 20 July 2018 (Journal of Laws of 2024, item 1571 ; Polish: Dz. U. z 2024 poz. 1571 t.j.) and who meet the following requirements:Required:

• A doctoral degree in biology, biotechnology, or bioinformatics
• Experience with basic molecular biology techniques, particularly protein identification using mass spectrometry
• Experience with confocal microscopy
• Good command of English, both spoken and written
• High motivation, enthusiasm, and independence in conducting research

Desirable:

• Experience in bioinformatics analyses

Specific Requirements

• Required documents

• Application form/letter of the candidate (email);
• Motivation letter (max. 2 pages), describing your research interests, career goals, and fit for this position
• Curriculum Vitae;
• Diplomas or certificates issued by colleges and universities attesting to education and degrees or titles held (in case of academic degrees obtained abroad – the documents must meet the equivalence criteria set out in Article 328 of the Act of 20 July 2018 Law on Higher Education and Science (Journal of Laws of 2024, item 1571 ; Polish: Dz. U. z 2024 poz. 1571 t.j.);
• Information on the Applicant’s research, teaching and organizational achievements,
• Consent to the processing of personal data as follows : In accordance with Article 6 (1) (a) of the General Data Protection Regulation of 27 April 2016. (OJ EU L 119/1 of 4 May 2016) I consent to the processing of personal data other than: first name, (first names) and surname; parents’ first names; date of birth; place of residence (mailing address); education; previous employment history, included in my job offer for the purpose of the current recruitment.”;

Languages ENGLISH Level GoodAdditional InformationBenefits

• an atmosphere of respect and cooperation
• supporting employees with disabilities
• flexible working hours
• funding for language learning
• co-financing of training and courses
• additional days off for education
• life insurance
• pension plan
• savings and investment fund
• preferential loans
• additional social benefits
• leisure-time funding
• subsidizing children’s vacations
• “13th” salary

Eligibility criteria

• Alignment of the candidate’s scientific profile with the job advertisement.
• Quality and quantity of the candidate’s scientific publications.
• Quality and quantity of the candidate’s scientific conference presentations.
• Experience gained through internships and participation in research projects.

Selection process

• Competition committee begins working no later than 14 days after the deadline for submission of documents.
• Formal evaluation of submitted proposals.
• Call to provide additional or missing documents if necessary.
• Selection of candidates for the interview stage.
• Interviews for candidates who meet the formal requirements.
• The chair of the competition committee announces the results and informs the candidates. This information will include justification with a reference to candidates’ strengths and weaknesses.

Additional comments

• A fixed-term employment contract initially for 6 months, with the possibility of extension for an additional 19 months.
• Monthly salary:~ 8.987,00 PLN gross
• Prospects for professional development:

• Support in developing a scientific career through co-authoring publications in renowned journals
• Assistance in writing grant applications for national and international projects
• Establishing collaborations with prestigious research centers worldwide

Work Location(s)Number of offers available 1 Company/Institute Center for Advanced Technologies, Adam Mickiewicz University, Poznan Country Poland City Poznań Postal Code 61-614 Street Uniwersytetu Poznaskiego 10 GeofieldContact State/ProvinceWielkopolska CityPoznań WebsiteStreetWieniawskiego 1 Postal Code61-712 E-Mail[email protected]STATUS: EXPIREDShare this page

Expected salary

Location

Poznań, wielkopolskie

Job date

Thu, 24 Jul 2025 22:51:14 GMT

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