Job title:
Postdoctoral researcher – Cancer biology
Company:
Job description
Offer DescriptionPositionThe Cancer Ecosystems and Metastasis Laboratory (CEMLab) at the Université Libre de Bruxelles (ULB), led by Panagiotis (Takis) Karras, is seeking a talented postdoc with a recent PhD or MD/PhD and experience in Cancer Biology/Biochemistry/Molecular Biology. The candidate will focus on a project to better characterize the drivers of cancer metastasis, profile the inter- and intra-tumor heterogeneity and plasticity combining mouse models and clinical samples. The successful applicant will join the ULB Faculty of Medicine and the Institute Jules Bordet within the campus.About CEMLabCEMLab investigates the cellular and molecular mechanisms driving the metastatic cascade and explores how the tumor ecosystem evolves in primary and metastatic organs. Our goal is to develop a comprehensive understanding of the molecular mechanisms and cell-cell interactions that favor metastasis and promote tumor outgrowth in distant organs.ProfileWe are seeking motivated candidates with a PhD in biomedical sciences, molecular biology, biochemistry, or a related field, and a strong background in cancer biology. Experience with mouse models is mandatory, while a background in melanoma biology is highly desirable. Candidates should have proven laboratory experience in molecular and cellular biology, a strong publication record in peer-reviewed journals, and the ability to work both independently and collaboratively as part of a team. Excellent organizational skills and strong interpersonal communication skills, both verbal and written, are essential.What we offerWe offer a full-time, 2-year funded contract with the possibility of extension, providing an engaging research environment that emphasizes quality, professionalism, and teamwork. The position offers the opportunity to work closely with physicians in a collaborative team setting and includes access to training courses for professional development. Immediate incorporation is available, and the salary will be commensurate with experience, following ULB’s pay scale.Want to join us?Interested candidates should send their application via email to Panagiotis Karras at , including a cover letter detailing relevant skills and experiences and a CV for assessment. Name and contact information of two references.DeadlineApplications will be accepted until the position is filled. Early submissions are encouraged as the position is available for immediate start.Relevant publicationsKarras P, Black J., McGranahan N. and Marine J-C. Genetic versus non-genetic driver mechanisms of metastasis. Nature 629, 543-554 (2024).Nowosad, A., Marine, J.-C. & Karras, P. Perivascular niches: critical hubs in cancer evolution. Trends Cancer (2023).Karras, P. et al. A cellular hierarchy in melanoma uncouples growth and metastasis. Nature610, 190-198 (2022).X. Li, P. Karras, R. Torres, F. Rambow, J.v.d Oord, J.C. Marine, L. Kos. Disseminated Melanoma Cells Transdifferentiate into Endothelial Cells in Intravascular Niches at Metastatic Sites. Cell Rep.31, (2020).Karras, P.et al. p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors. Cancer Cell (2019).Where to apply E-mail[email protected]RequirementsResearch Field Medical sciences » Cancer research Education Level PhD or equivalentLanguages ENGLISH Level ExcellentResearch Field Medical sciences » Cancer researchBiological sciences » BiologyAdditional InformationWork Location(s)Number of offers available 1 Company/Institute Universite libre de Bruxelles Country Belgium City Brussels GeofieldContact State/ProvinceBrussels-Capital Region CityBrussels WebsiteStreetRoute de Lennik 808STATUS: EXPIREDShare this page
Expected salary
Location
Bruxelles
Job date
Sun, 02 Feb 2025 05:39:42 GMT
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